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Results: 1 through 50 of 116 (0.265 secs)
You searched for: subject:"molecular biology"
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[texts]Identification of five patterns of nucleosome positioning that globally describe transcription factor function - Kazumitsu Maehara
Following the binding of transcription factors (TF) to specific regions, chromatin remodeling including alterations in nucleosome positioning (NP) occurs. These changes in NP cause selective gene expression to determine cell function. However whether specific NP patterns upon TF binding determine the transcriptional regulation such as gene activation or suppression is unclear. Here we identified five patterns of NP around TF binding sites (TFBSs) using fixed MNase-Seq analysis...
Keywords: Molecular Biology
Downloads: 6
[texts]Water and the biology of *prions* and plaques - Graham K Steel
This is an attempt to account for the insolubility and/or aggregation of prions and plaques in terms of a model of water consisting of an equilibrium between high density and low density microdomains. Hydrophobic molecules, including proteins, accumulate selectively into stable populations, enriched in high density water, at charged sites on biopolymers. In enriched high density water, proteins are probably partially unfolded and may precipitate out when released...
Keywords: Molecular Biology
Downloads: 7
[texts]Differentiation-dependent telomeric long non-coding transcription in a model of skeletal myogenesis - Scott Brouilette
Telomeres comprise the distal ends of eukaryotic chromosomes, serve to maintain genomic integrity and are extended by the ribonucleoprotein telomerase. Recent evidence indicates that telomeres are transcribed to generate long non-coding RNAs (lncRNAs) and that these transcripts (TERRA) may inhibit telomerase activity. In this study we assessed telomerase activity and telomeric lncRNA expression in a mouse model of skeletal myogenesis...
Keywords: Molecular Biology
Downloads: 7
[texts]ADP-ribose derived Nuclear ATP is Required for Chromatin Remodeling and Hormonal Gene Regulation - Roni H. G. Wright
Key nuclear processes in eukaryotes including DNA replication or repair and gene regulation require extensive chromatin remodeling catalyzed by energy consuming enzymes. How the energetic demands of such processes are ensured in response to rapid stimuli remains unclear. We have analyzed this question in the context of the massive gene regulation changes induced by progestins in breast cancer cells and found that ATP is generated in the cell nucleus via the hydrolysis of poly-ADP-ribose to ADP-r...
Keywords: Molecular Biology
Downloads: 17
[texts]How and where to look for tRNAs in Metazoan mitochondrial genomes, and what you might find when you get there - David Morrison
The ability to locate and annotate mitochondrial genes is an important practical issue, given the rapidly increasing number of mitogenomes appearing in the public databases. Unfortunately, tRNA genes in Metazoan mitochondria have proved to be problematic because they often vary in number (genes missing or duplicated) and also in the secondary structure of the transcribed tRNAs (T or D arms missing)...
Keywords: Molecular Biology
Downloads: 7
[texts]Neural lineage induction reveals multi-scale dynamics of 3D chromatin organization - Aleksandra Pekowska
Regulation of gene expression underlies cell identity. Chromatin structure and gene activity are linked at multiple levels, via positioning of genomic loci to transcriptionally permissive or repressive environments and by connecting cis-regulatory elements such as promoters and enhancers. However, the genome-wide dynamics of these processes during cell differentiation has not been characterized. Using tethered chromatin conformation capture (TCC) sequencing we determined global three-dimensional...
Keywords: Molecular Biology
Downloads: 9
[texts]Molecular identification of four species of mussels from southern Chile by PCR-based nuclear markers:the potential use in studies involving plankton surveys (Volume v. 17, no. 4-5 (1998))

Keywords: molecular biology
Downloads: 96
[texts]Reagent contamination can critically impact sequence-based microbiome analyses - Susannah Salter
The study of microbial communities has been revolutionised in recent years by the widespread adoption of culture independent analytical techniques such as 16S rRNA gene sequencing and metagenomics. One potential confounder of these sequence-based approaches is the presence of contamination in DNA extraction kits and other laboratory reagents. In this study we demonstrate that contaminating DNA is ubiquitous in commonly used DNA extraction kits, varies greatly in composition between different kit...
Keywords: Molecular Biology
Downloads: 25
[texts]A genome-wide analysis of Cas9 binding specificity using ChIP-seq and targeted sequence capture - Henriette O'Geen
Clustered regularly interspaced short palindromic repeat (CRISPR) RNA-guided nucleases have gathered considerable excitement as a tool for genome engineering. However, questions remain about the specificity of their target site recognition. Most previous studies have examined predicted off-target binding sites that differ from the perfect target site by one to four mismatches, which represent only a subset of genomic regions...
Keywords: Molecular Biology
Downloads: 26
[texts]Conditional U1 Gene Silencing in Toxoplasma gondii - Manuela S Pieperhoff
In absence of powerful siRNA approaches, the functional characterisation of essential genes in apicomplexan parasites, such as Toxoplasma gondii or Plasmodium falciparum, relies on conditional mutagenesis systems. Here we present a novel strategy based on U1 snRNP-mediated gene silencing. U1 snRNP is critical in pre-mRNA splicing by defining the exon-intron boundaries. When a U1 recognition site is placed into the 3’-terminal exon or adjacent to the termination codon, pre-mRNA is cleaved at th...
Keywords: Molecular Biology
Downloads: 17
[movies]EC-Rhodnius
Embryonic cuticle in Rhodnius Prolixus
Keywords: Biochemistry; Molecular Biology; Insects
Downloads: 61
[texts]Scientific Questions for Scientific Thinkers - Sivashanmugam. P., Department of Biotechnology, Jamal Mohamed College, Tiruchirappalli
What will you do if no thing has divisibility, comparability, connectivity, disturbability, reorderability, substitutability, and satisfiability?
Keywords: Biochemistry; immunology; molecular biology
Downloads: 61
[texts]Molecular Biology Laboratory Manual - Denny R Randall
Molecular Biology Laboratory Manual still needs some amount of work keep looking for a finshed work
Keywords: Molecular Biology Laboratory Manual
Downloads: 617
[texts]Scientific Questions for Scientific Thinkers (issue 2) - Sivashamugam
What will you do if no thing has divisibility, comparability, connectivity, disturbability, reorderability, substitutability, and satisfiability?
Keywords: Molecular biology; Biochemistry
Downloads: 43
[texts]Molecular Biology Laboratory Manual - Denny R Randall
Molecular Biology Laboratory Manual, is a work in progress toward the end of the work it should answer most question from simple to complex
Keywords: Molecular Biology Laboratory Manual
Downloads: 10,882
[texts]The Molecular aspects of biological development - Pennsylvania State University. Biophysics Dept
Includes bibliographical references
Keywords: Molecular biology; Embryology
Downloads: 1,087
[texts]Clinical molecular genetics in the UK c.1975-c.2000 : the transcript of a witness seminar held by the History of Modern Biomedicine Research Group, Queen Mary, University of London, on 5 February 2013 - Jones, E. M
Includes bibliographical references and index
Keywords: Molecular Biology; Genetics
Downloads: 39
[texts]Worldwide Molecular Biology Enzymes Market By Application & Product Forecast to 2018
The global molecular biology enzymes, kits and reagents market is segmented by application, end users, products, and geographies. Molecular biology enzymes, kits and reagents find applications in a large number of fields of life science research. The application segments included in this report are cloning, epigenetics, PCR (polymerase chain reaction), restriction digestion, sequencing, and other applications...
Keywords: Molecular Biology Enzymes Market; Molecular Biology Enzymes Industry; Molecular Biology Enzymes Market Forecast; Molecular Biology Enzymes Market Trends
Downloads: 3
[movies]Molecular Biology, Genetics & Biochemistry.part10
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 351
[movies]Molecular Biology, Genetics & Biochemistry.part21
Molecular Biology, Genetics & Biochemistry.part21
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 101
[movies]Molecular Biology, Genetics & Biochemistry.part24
Molecular Biology, Genetics & Biochemistry.part24
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 105
[movies]Molecular Biology, Genetics & Biochemistry.part20
Molecular Biology, Genetics & Biochemistry.part20
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 107
[movies]Molecular Biology, Genetics & Biochemistry.part15
Molecular Biology, Genetics & Biochemistry.part15
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 144
[movies]Molecular Biology, Genetics & Biochemistry.part11
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 151
[movies]Molecular Biology, Genetics & Biochemistry.part12
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 346
[movies]Molecular Biology, Genetics & Biochemistry.part16_804
Molecular Biology, Genetics & Biochemistry.part16
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 143
[movies]Molecular Biology, Genetics & Biochemistry.part14.
Molecular Biology, Genetics & Biochemistry.part14.
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 191
[movies]Molecular Biology, Genetics & Biochemistry.part17
Molecular Biology, Genetics & Biochemistry.part17
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 91
[movies]Molecular Biology, Genetics & Biochemistry.part13
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 407
[movies]Molecular Biology, Genetics & Biochemistry.part06
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 336
[movies]Molecular Biology, Genetics & Biochemistry.part08
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 390
[movies]Molecular Biology, Genetics & Biochemistry.part03
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 399
[movies]Molecular Biology, Genetics & Biochemistry.part23
Molecular Biology, Genetics & Biochemistry.part23
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 78
[movies]Molecular Biology, Genetics & Biochemistry.part05
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 172
[movies]Molecular Biology, Genetics & Biochemistry.part07
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 520
[movies]Molecular Biology, Genetics & Biochemistry.part25
Molecular Biology, Genetics & Biochemistry.part25
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 81
[movies]Molecular Biology, Genetics & Biochemistry.part22
Molecular Biology, Genetics & Biochemistry.part22
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 81
[movies]Molecular Biology, Genetics & Biochemistry.part09
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 252
[texts]Scientific Questions for Scientific Thinkers - Sivashanmugam
What will you do if no thing has divisibility, comparability, connectivity, disturbability, reorderability, substitutability, and satisfiability?
Keywords: cell biology; Molecular biology; Biochemistry
Downloads: 67
[movies]Molecular Biology, Genetics & Biochemistry.part04
Molecular Biology, Genetics & Biochemistry
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 361
[movies]Molecular Biology, Genetics & Biochemistry.part19
Molecular Biology, Genetics & Biochemistry.part19
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 95
[movies]Molecular Biology, Genetics & Biochemistry.part18
Molecular Biology, Genetics & Biochemistry.part18
Keywords: Molecular Biology; Genetics; Biochemistry; Najeeb
Downloads: 129
[texts]Molecular Biology Enzymes Industry by Application - Forecast to 2018
Molecular Biology Enzymes, Kits, & Reagents Market by Application (Cloning, Epigenetics, PCR, Restriction Digestion, Sequencing), Product (Ligase, Phosphatase, Polymerase, Protease, Restriction Endonuclease, Reverse Transcriptase) - Global Forecast to 2018 added to ReportsnReports.comThe global molecular biology enzymes, kits and reagents market is segmented by application, end users, products, and geographies...
Keywords: Molecular Biology Enzymes; Molecular Biology Enzymes Market; Molecular Biology Enzymes Industry
Downloads: 12
[texts]Worldwide Molecular Biology Enzymes Market Research Report 2018 – Application and Product (Ligase, Phosphatase, Polymerase, Protease)
The World Health Organization estimates that the total aged population may rise from 605 million in 2000 (11% of the global population) to 2 billion by 2050, accounting for 22% of the global population. As this segment of the world population is more susceptible to chronic diseases, research into these ailments will become more significant, driving the growth of the molecular biology enzymes, kits & reagents market.  Inquire For Discount (Single User Report Price US $4650) @ http://www.reports...
Keywords: molecular biology enzymes; kits & reagents market; molecular biology enzymes; kits & reagents Industry; Global molecular biology enzymes; kits & reagents market
Downloads: 1
[movies]Book of life - Wellcome Library
This is a Wellcome Trust News Release video about the work being carried out for the Human Genome Project (HUGO) at the Sanger Centre, Cambridge. Scientists there express their hopes of how medical science may benefit from this work. Spinal muscular atrophy, Alzheimer's disease, diabetes, heart disease and cancer are among the diseases targeted by HUGO. Other issues include the importance of the free release of data and concern about creating a genetic underclass if a price is put on the benefit...
Keywords: Genome; Molecular Biology; DNA; Human Genome Project; Molecular biology; Genome; Genome; Molecular Biology; DNA; Human Genome Project; Medical
Downloads: 362
[texts]Hydrogen/deuterium fractionation factors of the aqueous ligand of cobalt in Co(H[subscript]2O)6[superscript]2[superscript]+ and Co(II)-substituted carbonic anhydrase - Kassebaum, James Web
http://uf.catalog.fcla.edu/uf.jsp?st=UF023090432&ix=pm&I=0&V=D&pm=1
Keywords: Chemical Fractionation; Molecular Biology; Ligands; Carbonate Dehydrase
Downloads: 8
[texts]The chemical basis of life [microform] - Fraser-Harris, D. F. (David Fraser), 1867-1937
"Reprinted from the Canadian Medical Association Journal, February, 1912."
Keywords: Biologie moléculaire; Biochemistry; Biochimie; Molecular biology
Downloads: 236
[texts]The Developing heart : clinical implications of its molecular biology and physiology - Legato, Marianne J., 1935-
Includes index
Keywords: bub_upload; Heart; Molecular biology; Developmental biology
Downloads: 8
[texts]Molecular biology and agriculture : potential for future research : report of Western Experiment Station Collaborators Conference, March 13-16, 1968, Albany, California (Volume no.74-47) - Western Experiment Station Collaborators Conference (1968 : Albany, Calif.)
Cover title
Keywords: Molecular biology Congresses; Molecular genetics Congresses
Downloads: 48
[texts]Abrégé des leçons élémentaires de physique - Baume, Victor
An abstract on elementary physics
Keywords: Physics; Physics; Molecular Biology; Chemistry, Physical
Downloads: 137
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